Hematologists, Hematologist/Oncologists, Pediatric Hematologist/Oncologists, Pediatric Hematologists, Surgeons, Anesthesiologists, Intensivists, Critical Care Medicine Specialists, Emergency Medicine Clinicians, Primary Care Physicians, Registered Nurses
Factor VII Deficiency, Factor XIII Deficiency, Postpartum, Acquired Hemophilia, Rare Bleeding Disorders
|1.||Identify the clinical presentation and laboratory testing to appropriately diagnose unexplained or unusual bleeding in hospitalized patients||2.||Discuss treatment advances for rare bleeding disorders (RBDs), including new and emerging products|
|3.||Explain the evolution and purpose of RBD registries, specifically the RBD registry findings on the clinical phenotype levels and genotypic correlations in factor VII deficiency||4.||Provide appropriate education and guidance to patients with RBDs and their families|
|1.||Identify the clinical presentation and laboratory testing to appropriately diagnose unexplained or unusual bleeding in hospitalized patients|
|2.||Discuss treatment advances for rare bleeding disorders (RBDs), including new and emerging products|
|3.||Explain the evolution and purpose of RBD registries, specifically the RBD registry findings on the clinical phenotype levels and genotypic correlations in factor VII deficiency|
|4.||Provide appropriate education and guidance to patients with RBDs and their families|
The treatment of a patient with unexplained spontaneous bleeding typically follows an approach involving requisite knowledge of both normal hemostasis and common laboratory tests. Occasionally, however, a patient will present with an atypical scenario requiring the clinician to investigate more thoroughly to make a correct diagnosis and ultimately arrest bleeding.
Deficiencies of coagulation factors can be especially challenging for clinicians to recognize and treat due to their rarity in the general population. Although FVII deficiency is one of the more "common" rare bleeding disorders, its diagnosis and management can pose a challenge to healthcare practitioners, as it is a clinically heterogeneous disorder with a highly variable bleeding tendency.
Ongoing research continues to expand clinicians' understanding of the pathophysiology of unexplained bleeding due to factor deficiencies in hospitalized patients. Available and emerging clinical trials and registry data complement medical practice, resulting in early diagnosis and the application of new treatment options, as well as improved patient outcomes.
This interactive learning activity provides clinicians with the opportunity to build a case and, based on their choices, learn from expert commentary about the diagnosis and management of a rare coagulation factor deficiency.
This CME activity has been designed specifically to meet the educational needs of hospitalists, hematologists, HEM/ONCs, surgeons and anesthesiologists, intensivists and critical care medicine specialists, emergency medicine clinicians, primary care physicians, registered nurses and other healthcare providers interested in managing hospitalized patients with bleeding disorders such as acquired hemophilia and unexplained bleeding due to a coagulation factor deficiency.
Estimated Time to Complete Activity
Course Viewing Requirements
|Supported Browsers: |
Internet Explorer 8.0+ for Windows 2000, 2003, Vista, XP, Windows 7, Windows 8
Google Chrome 28.0+ for Windows, Mac OS, or Linux
Mozilla Firefox 23.0+ for Windows, Mac OS, or Linux
Safari 5.0+ for Mac OSX 10.5 and above
|Supported Phones & Tablets: |
Android 4.0.3 and above
iPhone/iPad with iOS 6.1 or above
|Name of Faculty or Presenter||Reported Financial Relationship|
|Amy D. Shapiro, MD||Has no real or apparent conflicts of interest to report.|
|Name of Planner or Manager||Reported Financial Relationship|
|PIM Clinical Reviewers: Laura Excell, ND, NP, MS, MA, LPC, NCC; Trace Hutchison, PharmD; Samantha Mattiucci, PharmD, CCMEP; and Jan Schultz, RN, MSN, CCMEP||Have no real or apparent conflicts of interest to report.|
|ECM: Patrick J. Crowley, MBA, Vice President/Managing Director; Cassie Rametta, BA, Program Director; Gay Boyle, MA, Chief Medical Writer||Have no real or apparent conflicts of interest to report.|