Hyponatremia Treatment Options: Management of High-Risk Patients

Optimizing Treatment for Hyponatremia
1 AMA PRA Category 1 Credit(s)
Launch Date:
April 30, 2013
Expiration Date:
The accreditation for this activity has expired.

Primary Audience:

Primary Care Physicians

Relevant Terms:


Mitchell H. Rosner, MD, FACP

Mitchell H. Rosner, MD, FACP
Chairman, Department of Medicine
Henry B. Mulholland Professor of Medicine
University of Virginia Health System
Charlottesville, VA

Mitchell Rosner, MD, FACP is the Henry B. Mulholland Professor of Medicine in the Division of Nephrology and Chairman for the Department of Medicine at the University of Virginia. He received his medical degree from the Medical College of Georgia, and completed his residency and a fellowship at the University of Virginia. He is board certified in internal medicine and nephrology.
Dr. Rosner is the fellowship program director for the Division of Nephrology and the associate program director for the medicine residency program at the University of Virginia School of Medicine. He is also the developer and director of the in-training examination for nephrology fellows.
Dr. Rosner has a strong interest in education. He is a member of the training program directors executive committee and the geriatric nephrology advisory board of the American Society of Nephrology, and serves on a number of national committees devoted to educational aspects of medical training. Dr. Rosner is the recipient of numerous honors including the University of Virginia All-University Teaching Award and the University Master Educator Award. 
His clinical practice focus is the medical care of patients with all forms of kidney disease—from acute kidney failure to end-stage kidney disease. His special interest in patients with polycystic kidney disease led Dr. Rosner to found the first regional clinic to specifically address the clinical management of patients with polycystic kidney disease. Dr. Rosner serves as the medical director for this multidisciplinary, patient-centered clinic that also provides selected patients the opportunity to enroll in clinical trials investigating novel therapies for this disease.
His research interests include the pathogenesis and management of disorders of sodium and water balance, the treatment of polycystic kidney disease, and the development of novel therapeutics for acute kidney injury. 
Dr. Rosner has published numerous research articles in peer-reviewed medical journals, and serves on the editorial boards of numerous journals including the American Journal of Kidney Disease and the Clinical Journal of the American Society of Nephrology.

Michael J. Cawley, BS, PharmD, RRT, CPFT

Michael J. Cawley, BS, PharmD, RRT, CPFT
Professor of Clinical Pharmacy
Philadelphia College of Pharmacy
University of the Sciences
Philadelphia, PA

Michael J. Cawley, BS, PharmD, RRT, CPFT  is Professor of Clinical Pharmacy at the Philadelphia College of Pharmacy, University of the Sciences, Philadelphia, PA (USA). Dr. Cawley graduated from the Philadelphia College of Pharmacy and Science receiving both his Bachelor and Doctor of Pharmacy degree's respectively. He completed a post-doctorate residency in Surgical Critical Care Pharmacy Practice at the Philadelphia College of Pharmacy and Science in conjunction with the Hospital of the University of Pennsylvania, Philadelphia, PA.

Dr. Cawley has greater than 25 years of experience in critical care including practicing as a Registered Respiratory Therapist and Critical Care Clinical Pharmacist. Areas of expertise include mechanical ventilation, critical care simulation training, aerosol therapy, sedation and analgesia, fluids and electrolytes, acid base disorders and infections in the critically ill patient.

Dr. Cawley is recognized for his leadership within the pharmacy profession including a member of the American Society of Health-System Pharmacists (ASHP) and Society of Critical Care Medicine (SCCM). He is a well published author, medical and legal consultant, pharmaceutical advisory board member and editorial reviewer for a number of medical journals including Pharmacotherapy, Clinical Therapeutics, Critical Care Medicine and editorial board member of Annals of Pharmacotherapy (Critical Care Section) Case Reports in Critical Care and Journal of Drug Intoxication and Detoxification. In addition, he is recognized as an outstanding educator and speaker receiving greater than 180 invitations as a presenter for national/international conferences and professional meetings.
1. Analyze the therapeutic options available to treat hyponatremia in hospitalized patients
2. Describe when various therapeutic options should be utilized in the treatment of hyponatremia
3. Discuss the risks and benefits of the therapeutic options for the treatment of hyponatremia


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All persons in a position to control the content of a continuing medical education program sponsored by PCME are required to disclose any relevant financial relationships with any commercial interest to PCME, as well as to learners. All conflicts are identified and resolved by PCME in accordance with the Standards for Commercial Support in advance of delivery of the activity to learners. Disclosures will be made known to the participants prior to the activity.
The content of this activity was vetted by an external medical reviewer to assure objectivity and that the activity is free of commercial bias.
Dr. Cawley has served as a speaker for Abbott, Amgen, Bristol-Myers Squibb, Biogen Idec, Centocor, Genentech, Lilly, Novartis, Pfizer, and UCB
Dr. Rosner has served as a consultant for Abbott Immunology, Alder, Amgen Corporation, AstraZeneca, Biotest, Bristol-Myers Squibb, Celgene, Centocor, Chelsea, Genentech, GlaxoSmithKline, Incyte, Lexicon Genetics, Lilly, Medimmune, MerckSerono, Novartis, NovoNordisk, Pfizer, Regeneron, Rigel, Sanofi-Aventis, and UCB.
Non-faculty content contributors and/or reviewers reported the following relevant financial relationships that they or their spouse/partner have with commercial interests: Barry Watkins, PhD; Bradley Pine; Blair St. Amand; Jay Katz, CCMEP; Dana Simpler, MD: Nothing to disclose 
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This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The Potomac Center for Medical Education (PCME) does not recommend the use of any agent outside of the labeled indications. 
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The Potomac Center for Medical Education designates this educational activity for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of the Potomac Center for Medical Education and Rockpointe. The Potomac Center for Medical Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
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In order to obtain credit for this activity, participants must complete and submit the activity evaluation and post-test. Participants must earn a score of 60% or higher in order to pass the post-test. Certificates of credit will be available to print from your user history page.
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  • Complete the post-test and activity evaluation.
  • Physicians who successfully complete the post-test and evaluation will receive CME credit. You must score with a 60% or higher on the post-test to receive credit for this activity.
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Release Date: April 30, 2013
Expiration Date: April 29, 2014

This program is supported through an educational grant from Otsuka America Pharmaceutical, Inc.
This continuing medical education activity is jointly sponsored by the and