Prurigo Nodularis: A Caucasian Adult Male With History of Uncontrolled PN and Associated Comorbidities
DermatologyNot Just Controlling the Itch: Recent Developments in Treating Prurigo Nodularis
0.25 AMA PRA Category 1 Credit(s) ™ 0.25 ANCC Contact Hours 0.25 ACPE
January 25, 2022
The accreditation for this activity has expired.
Primary Audience:
Dermatologists, specialty nurse practitioners, specialty physician assistants, and managed care pharmacists.
Relevant Terms:
Dermatology; pruritus; lesions; nodules; quality of life; angioedema; hives; off-label agents; wheals; skin; skin of color; differential diagnosis; prurigo nodularis
Chesahna Kindred, MD, MBA, FAAD
Assistant Professor of Dermatology
Howard University College of Medicine
Washington, DC
Kindred Hair & Skin Center
Columbia, MD
Dr Chesahna Kindred is a board-certified dermatologist, published research author, and national speaker. She was recently named “Physician of the Year” by the Daily Record. Dr Kindred grew up in South Central Los Angeles, an area of California known for its tough streets and strong community spirit, and a place where overcoming adversity was not simply a choice, but a way of life. It was this environment that planted the seed for Dr Kindred’s future in her field, cultivating a strong ambition and drive to serve her community, empowering people through beauty.
Growing up, she quickly garnered a reputation for her love of education and her desire to help others achieve their goals. It was this drive that led her to pursue a career within the field of dermatology. Dr Kindred began her studies at the University of Southern California where she received her Bachelor of Science with a minor in Spanish. She then relocated to Ohio where she continued to push herself in her educational pursuits, earning not just her MD degree, but also an MBA at the University of Cincinnati.
Dr Kindred was awarded a full scholarship as a Yates Fellow for the MBA program, where she was only the third person in the history of University of Cincinnati to receive the dual MD/MBA degree. She then took up her residency and fellowship at Howard University, an institution that pioneered Ethnic Dermatology. It was here that Dr Kindred gained her passion and focus on hair loss and ethnic skin.
Soon after graduating from her dermatology residency at Howard University, Dr Kindred became a leading dermatologist at MedStar Health in the Baltimore area. Five years later, she founded Kindred Hair & Skin Center in Columbia, Maryland, where she treats people of all ages and ethnicities.
Dr Kindred remains on the cutting edge of hair loss treatment, using 3 different methods of treating hair loss with growth factors, such as PRP, on a regular basis. Currently, she owns the first dermatology office with a full-service salon that specializes in hair loss, PeterKINdred Hair & Scalp Wellness Center. The stylist in the salon is Susan Peterkin, co-founder of the Natural Hair Industry Convention.
Locally, Dr Kindred is heavily involved in community service, often organizing health fairs, mentoring aspiring doctors, and working with local churches and community organizations to help educate and empower the community at large.
Within the field of dermatology, Dr Kindred is:
- Founder and President, Onyx Medical Society, a society of the National Medical Association
- Chair of the National Medical Association, Dermatology Section
- Fellow of the American Academy of Dermatology (FAAD)
- Member of the Women’s Dermatological Society, American Society of Dermatologic Surgery, Maryland Dermatologic Society, and Monumental Dermatology Society
Outside of dermatology, Dr Kindred is:
- Leader of the African American Community Roundtable, Health Committee
- Leader of Celebration Church Health & Wellness Ministry
- Deacon at Celebration Church at Columbia
Dr Kindred has been featured on:
- Disney’s Doc McStuffins
- WMAR Baltimore ABC News
- WJZ Baltimore CBS News
- WBFF Baltimore Fox News
- Dermatology Times
Dr Kindred has several publications concerning an array of dermatologic topics including co-writing chapters in leading dermatology textbooks. Her publications include but are not limited to hair loss, skin cancer, and treatments in patients with skin of color. Philosophically her focus of “Empowering through beauty” has resonated with patients worldwide. Understanding the desire people have to feel as beautiful outside as they do within, Dr Kindred helps them achieve the balance that allows people to feel complete. True beauty is not about vanity, but instead about empowering one’s self to have the confidence to live life to the fullest.
Shawn Kwatra, MD, FAAD
Associate Professor of Dermatology and Oncology
Director, Johns Hopkins Itch Center
Johns Hopkins University School of Medicine
Baltimore, MD
Dr Shawn Kwatra is an Assistant Professor of Dermatology and Director of the Johns Hopkins Itch Center at the Johns Hopkins University School of Medicine. He specializes in medical dermatology and is board certified by the American Board of Dermatology. Dr Kwatra’s areas of clinical expertise include, prurigo nodularis, chronic pruritus, atopic dermatitis, and dermatology for ethnic skin.
Dr Kwatra obtained his undergraduate degree from Duke University, medical training at Wake Forest University School of Medicine, and his dermatology residency training at the Johns Hopkins University School of Medicine.
Dr Kwatra’s primary clinical and translational research interest is in the pathogenesis and treatment of prurigo nodularis and chronic pruritus. He is a member of several professional organizations including the American Academy of Dermatology, the Society for Investigative Dermatology, and is currently serving on the Board of Directors of the Skin of Color Society.
| 1. | ANALYZE clinical data surrounding emerging treatments for PN | 2. | ASSESS the efficacy of standard, off-label treatments currently used for PN and residual burden of disease on patients |
| 3. | DEVELOP evaluation criteria for prurigo nodularis (PN) that incorporates characteristic features, including symptoms, presentation, and comorbidities | 4. | DEVISE a treatment plan that encourages long-term adherence |
| 1. | ANALYZE clinical data surrounding emerging treatments for PN |
| 2. | ASSESS the efficacy of standard, off-label treatments currently used for PN and residual burden of disease on patients |
| 3. | DEVELOP evaluation criteria for prurigo nodularis (PN) that incorporates characteristic features, including symptoms, presentation, and comorbidities |
| 4. | DEVISE a treatment plan that encourages long-term adherence |
SPONSORSHIP & SUPPORT
This educational activity is jointly provided by Global Education Group and Spire Learning.
This activity is supported by educational grants from Sanofi Genzyme and Regeneron Pharmaceuticals.
PROGRAM OVERVIEW
Prurigo nodularis (PN) is a chronic condition mediated by immune and neural dysregulation and presenting with highly pruritic, hyperkeratotic papules or nodules; the condition disproportionately affects African American patients compared to the general population. There are currently no FDA-approved therapies for the treatment of PN, leading to a high level of variability in clinical practice and the use of off-label agents; the current treatment landscape, or lack thereof, highlights the need for a multimodal approach to therapy and consideration of emerging agents. As a result, many health care professionals may be unaware of the standard, off-label treatments used, as well as the clinical data surrounding promising emerging agents for PN management and as a result, may miss opportunities to deliver evidence-based care. Join our expert faculty as they discuss patient scenarios utilizing methods to avoid missed opportunities for the care team, assess the clinical efficacy and safety of standard off-label, as well as emerging therapies, and ultimately devise effective treatment plans that encourage long-term adherence and address residual disease burden for patients with PN.*
*At the time of this activity launch, there were no therapies FDA-approved for the treatment of PN. As of September 2022, dupilumab became the first and only FDA-approved medication to specifically treat PN.
TARGET AUDIENCE
The target audience will be comprised of dermatologists, specialty nurse practitioners, specialty physician assistants, and managed care pharmacists.
LEARNING OBJECTIVES
Upon completion of this educational activity, learners should be better able to:
- ANALYZE clinical data surrounding emerging treatments for PN
- ASSESS the efficacy of standard, off-label treatments currently used for PN and residual burden of disease on patients
- DEVELOP evaluation criteria for prurigo nodularis (PN) that incorporates characteristic features, including symptoms, presentation, and comorbidities
- DEVISE a treatment plan that encourages long-term adherence
ACCREDITATION AND CREDIT DESIGNATION
Physician Accreditation Statement
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Global Education Group (Global) and Spire Learning, LLC. Global is accredited by the ACCME to provide continuing medical education for physicians.
Physician Credit Designation
Global Education Group designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Nursing Continuing Education
Global Education Group is accredited with distinction as a provider of nursing continuing professional development by the American Nurses Credentialing Center’s Commission on Accreditation.
This educational activity for 0.25 contact hour is provided by Global Education Group. Nurses should claim only the credit commensurate with the extent of their participation in the activity.
Pharmacist Accreditation Statement 
Global Education Group is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.
Credit Designation Statement
Global Education Group designates this continuing education activity for 0.25 contact hour(s) (0.025 CEUs) of the Accreditation Council for Pharmacy Education. (Universal Activity Number - 0530-9999-21-162-H01-P) This is a knowledge-based activity.
HOW TO RECEIVE CREDIT
There is no fee for this educational activity. To receive credit for your participation in this educational activity:
- Read the objectives and other introductory CME information
- Complete the preassessment prior to the start of the activity
- Participate in the prurigo nodularis case activity
- Complete the postassessment with a passing score of 70% and complete the evaluation at the conclusion of the activity
If you are seeking credit, you must complete the evaluation at the conclusion of the activity.
For information about the accreditation of this program, please contact Global at 303-395-1782 or cme@globaleducationgroup.com
CONFLICTS OF INTEREST STATEMENT
Global Education Group (Global) adheres to the policies and guidelines, including the Standards for Integrity and Independence in Accredited CE, set forth to providers by the Accreditation Council for Continuing Medical Education (ACCME) and all other professional organizations, as applicable, stating those activities where continuing education credits are awarded must be balanced, independent, objective, and scientifically rigorous. All persons in a position to control the content of an accredited continuing education program provided by Global are required to disclose all financial relationships with any ineligible company within the past 24 months to Global. All financial relationships reported are identified as relevant and mitigated by Global in accordance with the Standards for Integrity and Independence in Accredited CE in advance of delivery of the activity to learners. The content of this activity was vetted by Global to assure objectivity and that the activity is free of commercial bias.
All relevant financial relationships have been mitigated.
PLANNING COMMITTEE
Chesahna Kindred, MD, MBA, FAAD (Chair)
Assistant Professor of Dermatology
Howard University College of Medicine
Washington, DC
Kindred Hair & Skin Center
Columbia, MD
Disclosures:
Consulting Fees (eg, Advisory Board): Aerolase; Eli Lilly and Company; Sun Pharmaceuticals; UCB, Inc
Speakers’ Bureau: Aerolase; Eli Lilly and Company; Novartis Pharmaceuticals Corporation; Nutrafol; Sun Pharmaceuticals; UCB, Inc
Shawn Kwatra, MD, FAAD
Associate Professor of Dermatology and Oncology
Director, Johns Hopkins Itch Center
Johns Hopkins University School of Medicine
Baltimore, MD
Disclosures:
Consulting Fees (eg, Advisory Board): AbbVie Inc; Celldex Therapeutics; Galderma; Incyte Corp; Kiniksa Pharmaceuticals; Novartis Pharmaceuticals Corp; Pfizer Inc; Regeneron Pharmaceuticals; Sanofi
Contracted Research: Galderma; Kiniksa Pharmaceuticals; Pfizer Inc; Sanofi
EDUCATIONAL PLANNING COMMITTEE
Global Education Group
Rhys Williams, MSN, FNP-C, RN; Lindsay Borvansky; Andrea Funk; Liddy Knight; Ashley Cann; No relevant financial relationships with any commercial interests.
Spire Learning
Andrew Kim, Kimberly Miniter, and Mary Simmons have nothing to disclose.
Reviewer
Lindsay Borvansky: No relevant financial relationships with any commercial interests.
OFF-LABEL STATEMENT
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Global Education Group (Global) and Spire Learning do not recommend the use of any agent outside of the labeled indications.
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Disclaimer
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.
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COPYRIGHT INFORMATION:
Copyright © 2022 by Spire Learning, LLC and Global Education Group. All rights reserved including translation into other languages. No part of this publication or activity may be reproduced or transmitted in any form, by any means, without prior written permission of Spire Learning, LLC.
COURSE VIEWING REQUIREMENTS
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| Additional Recommendations and Requirements | |
| Display Resolution & Color Depth | Resolution - 960 X 768 minimum - 1024 X 768 recommended min. Color Depth - 8 bits (256 colors) minimum - 16 bits (High colors) minimum |
| Audio | - Microphone - Speakers or headphones - Audio recording support |
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